88 THE ESSEX NATURALIST. when he was apparently released from his apprenticeship bond and proceeded in 1734 to pursue his medical studies in Edinburgh. Here he took his degree of Doctor of Medicine, and made his way to London, and on 29 October, 1736, to further qualify himself, he entered as a student at St. Thomas's Hospital. Having estab- lished a fair practice, he took a house in White Hart Court, Gracechurch Street, in 1740, and as he had previously lodged at Robert Bell's in Gracechurch Street he had no doubt been influenced in his selection of both lodging and house by their close proximity to the Friends' Meeting House in Gracechurch Street, whose members and attendants were certainly among his first patients. Prior to settlement in his new house Fothergill had made a Continental tour, which cost him £44 for the twelve weeks of its continuance. His fees for the year had amounted to 105 guineas. His progress was slow, and his income small, but epidemics of throat disorder swept over London in the autumns of 1747 and 1748, and were fatal to large numbers of people, especially children. Fothergill saw his opportunity, made a careful study of the disease, and, discarding the usual methods of bleeding and purging, was very successful in his treatment, which made especial use of cinchona bark. Fired by his success he wrote and published in 1748, "An Account of the Sore Throat attended with ulcers." This book achieved a wide circulation, and many editions were issued; his reputation was made, and almost immediately a large and lucrative practice rewarded him. Also at this time he became concerned about the terrible ravages of smallpox and, influenced probably by Baron Dimsdale and the Essex Suttons, who had introduced an improved method, he became convinced of the benefits of inoculation, and in a letter to his brother concerning an out- break, writes:— "I should earnestly advise inoculation, 'tis an operation "easily to be performed and in the manner I am going to "direct it is seldom with any ill effects. "In common, those who have it in this way get through "without the least danger. A common sewing thread, of "moderate thickness, may be drawn through a ripe spot "in such a manner as that some part of the thread may be a "little moistened with the matter. Then with the point of "a needle make a small scratch on the skin a little below