12 Britain", published in London (4 vols 1724-27), as to the effects of Ague in the marshlands of Essex at that period, but I suppose there is this amount of truth in the stories, viz:— that there was a considerable mortality among persons going to live at such places as Fobbing, Mucking, Canvey Island, etc. I believe there is practically no Ague now-a-days in South Essex: anyhow there is none in Aveley. How has this change come about? The marshes have been drained for the last 300 years in the same manner as now." Clearly in the 17th century Malaria or Ague as it was called was not uncommon in parts of Essex. The mosquito species concerned was Anopheles maculipennis. There have been no cases of indigenous as opposed to introduced Malaria for many decades. It seems to have died out in Britain as a result of a fortuitous separation of the infected fly from its host. For Malaria to prevail, Plasmodium needs to be constantly taken in by the mosquito from one infected person and then injected into another in mosquito saliva. Since mosquitoes do not pass the infection to their own offspring the process of transfer needs to be continuous. As housing conditions improved the mosquitoes were dissuaded from hibernating in houses which had been their habit in the last century. Hence the disease diminished and disappeared. There have been outbreaks of Malaria in this century but it has been introduced from overseas: for example during the Great War, when soldiers returning from areas with a high